This has been discussed before to some degree, but how does different sized appendages affect movement?  Here’s my example:  I have Klippel–Trénaunay syndrome (KTS) and one of the traits of this syndrome is muscle/bone hypertrophy.  My right side of my body is an inch larger than my left.  This is noticeable in all of my extremities; my hips and arms are quite apparent (I can put an inch mat under my left leg and my hips look more aligned).  I’m now aware that parts of my body tend to get tighter than the opposite side, and I’ve been tackling this issues now since I attended the mob seminar a few years ago, but I tend to get tweaks frequently (usually left side of lower back) and was curious how this size difference impacts heavy loading or movements with speed knowing my body is slightly lopsided.  In addition, locking weights out overhead or in bench is always harder on my right side since it’s traveling farther.